Prenatal diagnosis of a de novo non-fluorescent Y chromosome.
نویسندگان
چکیده
We report a case with non-mosaic Yq-, missing the fluorescent segment, and detected as a fetus studied for advanced maternal age. The father had a Y chromosome of average size and paternity was established wih a plausibility of 97.7% by HLA and erythrocyte antigen typing. The child had a normal male antigen typing. The child had a normal male phenotype at delivery and developmental milestones were normal through the first year of life. The Yq- showed no mitotic instability since it was retained in foreskin culture for its in vitro lifetime of 60 population doublings.
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عنوان ژورنال:
- Journal of medical genetics
دوره 17 4 شماره
صفحات -
تاریخ انتشار 1980